US Border Patrol agents were searching the Rio Grande River on Tuesday a 2-year-old girl who went missing while crossing the waterway with her mother, officials said.

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Agents from the Del Rio Station Border Patrol Search Operations began wading through the river Monday night when a woman from Haiti alerted them that her child, a native of Brazil, had disappeared in the river, according to US Customs and Border Protection.

“Any time a child is lost it is a tragic event,” said Del Rio Sector Chief Patrol Agent Raul L. Ortiz.

“I can not imagine the anguish the parents of this young girl must be feeling and I hope our search efforts pay off with a positive outcome.”

The mother was detained by agents from the Del Rio Border Patrol Station on Monday shortly after she crossed the river from Mexico.

After telling the agents about the missing child, a Border Patrol Search Trauma and Rescue unit began scouring the waters.

Border Patrol — in conjunction with law enforcement teams from Ciudad Acuna, Mexico — were continuing the search Tuesday night.